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Found 1,838 Skills
Write a systematic review protocol into `output/PROTOCOL.md` (databases, queries, inclusion/exclusion, time window, extraction fields). **Trigger**: protocol, PRISMA, systematic review, inclusion/exclusion, 检索式, 纳入排除. **Use when**: systematic review pipeline 的起点（C1），需要先锁定 protocol 再开始 screening/extraction。 **Skip if**: 不是做 systematic review（或 protocol 已经锁定且不允许修改）。 **Network**: none. **Guardrail**: protocol 必须包含可执行的检索与筛选规则；需要 HUMAN 签字后才能进入 screening。
Production-safe error handling that logs full details server-side while exposing only generic, safe messages to users. Prevents information leakage of database strings, file paths, stack traces, and API keys.
Comprehensive guide for production-ready Python backend development and software architecture at scale. Use when designing APIs, building backend services, creating microservices, structuring Python projects, implementing database patterns, writing async code, or any Python backend/server-side development task. Covers Clean Architecture, Domain-Driven Design, Event-Driven Architecture, FastAPI/Django patterns, database design, caching strategies, observability, security, testing strategies, and deployment patterns for high-scale production systems.
bkend.ai platform onboarding and core concepts guide. Covers MCP setup, resource hierarchy (Org->Project->Environment), Tenant vs User model, and first project creation. Use proactively when user is new to bkend or asks about initial setup. Triggers: bkend setup, first project, bkend start, MCP connect, bkend 시작, 처음, 설정, MCP 연결, 프로젝트 생성, bkend始め方, 初期設定, MCP接続, bkend入门, 初始设置, MCP连接, configuracion bkend, primer proyecto, configuration bkend, premier projet, bkend Einrichtung, erstes Projekt, configurazione bkend, primo progetto Do NOT use for: specific database/auth/storage operations (use domain-specific skills), enterprise infrastructure (use infra-architect).
FaasJS best practices - file conventions, defineFunc, database(knex).
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
Mandatory incident fix verification with observables. Invoke after: applying production fixes, before declaring incidents resolved, when someone says 'I think that fixed it'. Requires log entries, metric changes, and database state confirmation.
Use this skill when spreadsheet files are the primary input or output. This means the user wants to: open, read, edit, or repair existing .xlsx, .xlsm, .csv, or .tsv files (e.g., add columns, calculate formulas, format, create charts, clean messy data); create new spreadsheets from scratch or from other data sources; or convert between spreadsheet file formats. Trigger this especially when the user references a spreadsheet file by name or path—even casually (such as "the xlsx in my downloads")—and wants to process it or generate content from it. It's also used to clean or reorganize messy tabular data files (rows with incorrect formatting, misaligned headers, garbage data) into proper spreadsheets. The deliverable must be a spreadsheet file. Do not trigger this when the primary deliverable is a Word document, HTML report, standalone Python script, database pipeline, or Google Sheets API integration, even if tabular data is involved.
Analyzes impact of proposed changes on existing systems (brownfield projects) with delta spec validation. Trigger terms: change impact, impact analysis, brownfield, delta spec, change proposal, change management, existing system analysis, integration impact, breaking changes, dependency analysis, affected components, migration plan, risk assessment, brownfield change. Provides comprehensive change analysis for existing systems: - Affected component identification - Breaking change detection - Dependency graph updates - Integration point impact - Database migration analysis - API compatibility checks - Risk assessment and mitigation strategies - Migration plan recommendations Use when: proposing changes to existing systems, analyzing brownfield integration, or validating delta specifications.
Provides comprehensive code review capability for NestJS applications, analyzing controllers, services, modules, guards, interceptors, pipes, dependency injection, and database integration patterns. Use when reviewing NestJS code changes, before merging pull requests, after implementing new features, or for architecture validation. Triggers on "review NestJS code", "NestJS code review", "check my NestJS controller/service".
LOAD THIS SKILL when: writing unit tests, TRPC integration tests, or E2E tests. Covers Vitest patterns, Effect service testing, PGlite database testing, and Playwright E2E.
UI/UX design intelligence with searchable database of patterns, styles, and stacks.