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Found 196 Skills
Integrate and analyze multiple omics datasets (transcriptomics, proteomics, epigenomics, genomics, metabolomics) for systems biology and precision medicine. Performs cross-omics correlation, multi-omics clustering (MOFA+, NMF), pathway-level integration, and sample matching. Coordinates ToolUniverse skills for expression data (RNA-seq), epigenomics (methylation, ChIP-seq), variants (SNVs, CNVs), protein interactions, and pathway enrichment. Use when analyzing multi-omics datasets, performing integrative analysis, discovering multi-omics biomarkers, studying disease mechanisms across molecular layers, or conducting systems biology research that requires coordinated analysis of transcriptome, genome, epigenome, proteome, and metabolome data.
Go backend development standards using DDD architecture, ent ORM, fx DI, and kiwi-lib utilities. Covers project structure, domain design, API/application/infrastructure layers, database workflow, and coding requirements.
Comprehensive guide and toolkit for creating advanced LINE Flex Messages with complex layouts, video integration, and implementing reliable API retry mechanisms with X-Line-Retry-Key. Use when creating sophisticated Bot UIs, handling high-load messaging, or designing robust communication layers for LINE.
Design Laravel app architecture with services, repositories, actions, and clean code patterns. Use when structuring projects, creating services, implementing DI, or organizing code layers.
Effect v4 (beta) development and v3 → v4 migration guidance. Use when building new Effect v4 code or upgrading from v3, including API renames, behavior changes, before/after examples, and v4-specific patterns for services, layers, generators, yieldable, error handling, and schema codecs.
Use this skill when building dbt models, designing semantic layers, defining metrics, creating self-serve analytics, or structuring a data warehouse for analyst consumption. Triggers on dbt project setup, model layering (staging, intermediate, marts), ref() and source() usage, YAML schema definitions, metrics definitions, semantic layer configuration, dimensional modeling, slowly changing dimensions, data testing, and any task requiring analytics engineering best practices.
Implementation guide for Syncfusion WinForms Maps control - a geographical data visualization component that displays statistical and regional data using shape files, bubbles, markers, and interactive features. Use this when working with WinForms Maps, geographical maps in Windows Forms, shape file visualization, choropleth maps, or bubble maps. This skill covers map layers, zooming/panning, geographical data binding, ESRI shape files, and building location-based desktop applications with interactive maps.
Guide fee disclosure compliance across advisory, brokerage, fund, and retirement plan contexts. Use when the user asks about Form ADV Item 5 fee schedules, prospectus fee table format, Reg BI cost disclosure obligations, 12b-1 fee transparency, revenue sharing arrangements, wrap fee program costs, or ERISA 408(b)(2) service provider fee disclosure. Also trigger when users mention 'hidden fees', 'total cost to the client', 'are we disclosing all layers of fees', 'expense ratio comparison', 'fee billing in advance vs arrears', 'share class selection', 'indirect compensation', or ask whether fee disclosures are complete and compliant.
Sticky and fixed positioning keeps critical UI persistent as the user scrolls — headers at the top, toolbars at the bottom on mobile. Use deliberately: too many fixed layers create visual noise and reduce content area. Use when designing navigation headers, bottom toolbars, floating action buttons, or table column headers.
Scaffold and architect custom Frappe apps including app structure, hooks, background jobs, service layers, and production hardening. Use when creating new apps, setting up app architecture, or implementing cross-cutting patterns like caching, logging, and error handling.
Execute web cache deception attacks by exploiting path normalization discrepancies between CDN caching layers and origin servers to cache and retrieve sensitive authenticated content.
Minimal product pre-launch landing page with email capture, logo, and decorative layers