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Found 381 Skills
Generate and publish blog posts from any project to kelegele/agent-blog. ZERO DEPENDENCIES — does NOT require Node.js, pnpm, git, or any local build tools. Works with only a browser and a GitHub token. Triggers on: "写篇博客", "blog this", "发博文", "publish blog", "把项目写成文章", "写篇文章", "blog it", "post article", "新文章", "new blog post", "blog this project", "发一篇博文", "写一篇博文", "blog post about this", "edit blog post", "修改文章", "更新博文", "edit article". Collects project context, collaborates on outline, writes Markdown with correct frontmatter, validates article format, generates a standalone HTML preview by reading live blog source, manages draft/review/publish flow. Pushes to kelegele/agent-blog main branch. Vercel auto-deploys on push. Use this skill whenever the user expresses intent to write about their current work as a blog post.
Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.
Migrate to Cloudflare Workers from AWS Lambda, Vercel, Express, and Node.js. Use when porting existing applications to the edge, adapting serverless functions, or resolving Node.js API compatibility issues.
Create and manage Oodle log-based metric rules — extract metrics from log streams using filter expressions and groupBy labels.
Production backend systems development. Stack: Node.js/TypeScript, Python, Go, Rust | NestJS, FastAPI, Django, Express | PostgreSQL, MongoDB, Redis. Capabilities: REST/GraphQL/gRPC APIs, OAuth 2.1/JWT auth, OWASP security, microservices, caching, load balancing, Docker/K8s deployment. Actions: design, build, implement, secure, optimize, deploy, test APIs and services. Keywords: API design, REST, GraphQL, gRPC, authentication, OAuth, JWT, RBAC, database, PostgreSQL, MongoDB, Redis, caching, microservices, Docker, Kubernetes, CI/CD, OWASP, security, performance, scalability, NestJS, FastAPI, Express, middleware, rate limiting. Use when: designing APIs, implementing auth/authz, optimizing queries, building microservices, securing endpoints, deploying containers, setting up CI/CD.
Retrieves gene expression and omics datasets from ArrayExpress and BioStudies with gene disambiguation, experiment quality assessment, and structured reports. Creates comprehensive dataset profiles with metadata, sample information, and download links. Use when users need expression data, omics datasets, or mention ArrayExpress (E-MTAB, E-GEOD) or BioStudies (S-BSST) accessions.
Quality control metrics and filtering thresholds for protein design. Use this skill when: (1) Evaluating design quality for binding, expression, or structure, (2) Setting filtering thresholds for pLDDT, ipTM, PAE, (3) Checking sequence liabilities (cysteines, deamidation, polybasic clusters), (4) Creating multi-stage filtering pipelines, (5) Computing PyRosetta interface metrics (dG, SC, dSASA), (6) Checking biophysical properties (instability, GRAVY, pI), (7) Ranking designs with composite scoring. This skill provides research-backed thresholds from binder design competitions and published benchmarks.
Comprehensive DeepResearch methodology for conducting rigorous, traceable research projects with quality gates, structured analysis, and decision-ready deliverables. Use when (1) Conducting deep research projects requiring evidence-based analysis, (2) Managing research progress with quality gates and artifacts, (3) Producing research reports with traceable sources and structured reasoning, (4) Applying OSINT verification techniques, (5) Using structured analytic techniques (ACH, Key Assumptions Check, Red Team), (6) Expressing uncertainty and confidence in research findings, (7) Ensuring research deliverables meet intelligence tradecraft standards (ICD 203/206/208)
Integrate crypto payments into any web application with PayRam. Self-hosted payment gateway — no KYC, no signup, no third-party custody. Accept USDT, USDC, Bitcoin, ETH in under 10 minutes. Works with Express, Next.js, FastAPI, Laravel, Gin, Spring Boot. Drop-in replacement for Stripe/PayPal for crypto. Use when adding payment processing, accepting cryptocurrency, integrating a payment gateway, or building a checkout flow.
Better Auth — framework-agnostic TypeScript authentication & authorization library. Covers setup, email/password, social OAuth (40+ providers), passkeys, magic links, 2FA, organizations, sessions, plugins, admin, hooks, and security hardening. Use when implementing auth with Better Auth: configuring auth instances, adding providers, setting up database adapters (Prisma, Drizzle, PostgreSQL, MySQL, SQLite, MongoDB), integrating with frameworks (Next.js, Nuxt, SvelteKit, Astro, Hono, Express, Elysia, Fastify, Expo), managing sessions, or extending with plugins.
Convert photos (people, pets, objects, logos) into 4 animated GIF stickers with captions. Use when: user wants to create cartoon stickers, GIF expressions, emoji packs, animated avatars, or convert photos to Funko Pop / Pop Mart blind box style animations. Triggers: sticker, GIF, cartoon, emoji, expression pack, avatar animation.
Grafana Alloy OpenTelemetry collector and telemetry pipeline configuration. Covers the Alloy configuration language (blocks, attributes, expressions), components for collecting metrics/logs/traces/profiles, sending data to Grafana Cloud/Prometheus/Loki/Tempo, clustering, Fleet Management remote config, and building telemetry pipelines. Use when configuring Alloy, writing Alloy config files (.alloy), building data collection pipelines, setting up scraping, or troubleshooting Alloy deployments.