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Found 1,832 Skills
Comprehensive molecular biology toolkit. Use for sequence manipulation, file parsing (FASTA/GenBank/PDB), phylogenetics, and programmatic NCBI/PubMed access (Bio.Entrez). Best for batch processing, custom bioinformatics pipelines, BLAST automation. For quick lookups use gget; for multi-service integration use bioservices.
DNAnexus cloud genomics platform. Build apps/applets, manage data (upload/download), dxpy Python SDK, run workflows, FASTQ/BAM/VCF, for genomics pipeline development and execution.
Standard single-cell RNA-seq analysis pipeline. Use for QC, normalization, dimensionality reduction (PCA/UMAP/t-SNE), clustering, differential expression, and visualization. Best for exploratory scRNA-seq analysis with established workflows. For deep learning models use scvi-tools; for data format questions use anndata.
Fast in-memory DataFrame library for datasets that fit in RAM. Use when pandas is too slow but data still fits in memory. Lazy evaluation, parallel execution, Apache Arrow backend. Best for 1-100GB datasets, ETL pipelines, faster pandas replacement. For larger-than-RAM data use dask or vaex.
Spectral similarity and compound identification for metabolomics. Use for comparing mass spectra, computing similarity scores (cosine, modified cosine), and identifying unknown compounds from spectral libraries. Best for metabolite identification, spectral matching, library searching. For full LC-MS/MS proteomics pipelines use pyopenms.
Lightweight WSI tile extraction and preprocessing. Use for basic slide processing tissue detection, tile extraction, stain normalization for H&E images. Best for simple pipelines, dataset preparation, quick tile-based analysis. For advanced spatial proteomics, multiplexed imaging, or deep learning pipelines use pathml.
Use when doing any dbt work - building or modifying models, debugging errors, exploring unfamiliar data sources, writing tests, or evaluating impact of changes. Use for analytics pipelines, data transformations, and data modeling.
Reactive streams and event-driven programming in Golang using samber/ro — ReactiveX implementation with 150+ type-safe operators, cold/hot observables, 5 subject types (Publish, Behavior, Replay, Async, Unicast), declarative pipelines via Pipe, 40+ plugins (HTTP, cron, fsnotify, JSON, logging), automatic backpressure, error propagation, and Go context integration. Apply when using or adopting samber/ro, when the codebase imports github.com/samber/ro, or when building asynchronous event-driven pipelines, real-time data processing, streams, or reactive architectures in Go. Not for finite slice transforms (-> See golang-samber-lo skill).
Use when setting up CI/CD pipelines, containerizing applications, deploying to Kubernetes, or writing infrastructure as code. DevOps & Deployment covers GitHub Actions, Docker, Helm, and Terraform patterns.
Monadic types for Golang using samber/mo — Option, Result, Either, Future, IO, Task, and State types for type-safe nullable values, error handling, and functional composition with pipeline sub-packages. Apply when using or adopting samber/mo, when the codebase imports `github.com/samber/mo`, or when considering functional programming patterns as a safety design for Golang.
Machine learning in Python with scikit-learn. Use when working with supervised learning (classification, regression), unsupervised learning (clustering, dimensionality reduction), model evaluation, hyperparameter tuning, preprocessing, or building ML pipelines. Provides comprehensive reference documentation for algorithms, preprocessing techniques, pipelines, and best practices.
Build resilient data ingestion pipelines from APIs. Use when creating scripts that fetch paginated data from external APIs (Twitter, exchanges, any REST API) and need to track progress, avoid duplicates, handle rate limits, and support both incremental updates and historical backfills. Triggers: 'ingest data from API', 'pull tweets', 'fetch historical data', 'sync from X', 'build a data pipeline', 'fetch without re-downloading', 'resume the download', 'backfill older data'. NOT for: simple one-shot API calls, websocket/streaming connections, file downloads, or APIs without pagination.