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Found 638 Skills
A pattern for generating higher-quality output by iterating against explicit scoring criteria. Use for headlines, CTAs, landing page copy, social content, ad copy — anything where quality matters. Generate → Evaluate → Diagnose → Improve → Repeat.
Expert patterns for HubSpot CRM integration including OAuth authentication, CRM objects, associations, batch operations, webhooks, and custom objects. Covers Node.js and Python SDKs. Use when: hubspot, hubspot api, hubspot crm, hubspot integration, contacts api.
Guide for implementing James Shore's Nullables pattern and A-Frame architecture for testing without mocks. Use when implementing or refactoring code to follow patterns of: (1) Separating logic, infrastructure, and application layers, (2) Creating testable infrastructure with create/createNull factory methods, (3) Writing narrow, sociable, state-based tests without mocks, (4) Implementing value objects, (5) Building infrastructure wrappers that use embedded stubs, or (6) Designing dependency injection through static factory methods.
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
Journalism source verification and fact-checking workflows. Use when verifying claims, checking source credibility, investigating social media accounts, reverse image searching, or building verification trails. Essential for reporters, fact-checkers, and researchers working with unverified information.
Integrate Cartridge Controller into native mobile applications (iOS, Android, React Native) and web wrappers (Capacitor). Use when building mobile games or apps that need Controller wallet functionality with local keypair signing. Covers SessionConnector for native auth flows, Controller.c FFI bindings, passkey configuration with Apple App Site Association, and platform-specific setup.
Comprehensive immune repertoire analysis for T-cell and B-cell receptor sequencing data. Analyze TCR/BCR repertoires to assess clonality, diversity, V(D)J gene usage, CDR3 characteristics, convergence, and predict epitope specificity. Integrate with single-cell data for clonotype-phenotype associations. Use for adaptive immune response profiling, cancer immunotherapy research, vaccine response assessment, autoimmune disease studies, or repertoire diversity analysis in immunology research.
Interpret genetic variants (SNPs) from GWAS studies by aggregating evidence from multiple databases (GWAS Catalog, Open Targets Genetics, ClinVar). Retrieves variant annotations, GWAS trait associations, fine-mapping evidence, locus-to-gene predictions, and clinical significance. Use when asked to interpret a SNP by rsID, find disease associations for a variant, assess clinical significance, or answer questions like "What diseases is rs429358 associated with?" or "Interpret rs7903146".
Discover genes associated with diseases and traits using GWAS data from the GWAS Catalog (500,000+ associations) and Open Targets Genetics (L2G predictions). Identifies genetic risk factors, prioritizes causal genes via locus-to-gene scoring, and assesses druggability. Use when asked to find genes associated with a disease or trait, discover genetic risk factors, translate GWAS signals to gene targets, or answer questions like "What genes are associated with type 2 diabetes?"
Comprehensive computational validation of drug targets for early-stage drug discovery. Evaluates targets across 10 dimensions (disambiguation, disease association, druggability, chemical matter, clinical precedent, safety, pathway context, validation evidence, structural insights, validation roadmap) using 60+ ToolUniverse tools. Produces a quantitative Target Validation Score (0-100) with GO/NO-GO recommendation. Use when users ask about target validation, druggability assessment, target prioritization, or "is X a good drug target for Y?"
Compare GWAS studies, perform meta-analyses, and assess replication across cohorts. Integrates NHGRI-EBI GWAS Catalog and Open Targets Genetics to compare study designs, effect sizes, ancestry diversity, and heterogeneity statistics. Use when comparing GWAS studies for a trait, performing meta-analysis of genetic loci, assessing replication across cohorts, or exploring the genetic architecture of complex diseases.
Enrich contact, company, and influencer data using x402-protected APIs. Superior to generic web search for structured business data. USE FOR: - Enriching person profiles by email, LinkedIn URL, or name - Enriching companies by domain - Finding contact details (email, phone) with confidence scores - Scraping full LinkedIn profiles (experience, education, skills) - Searching for people or companies by criteria - Bulk enrichment operations (up to 10 at a time) - Verifying email deliverability before outreach - Enriching influencer/creator profiles across social platforms TRIGGERS: - "enrich", "lookup", "find info about", "research" - "who is [person]", "company profile for", "tell me about" - "find contact for", "get LinkedIn for", "get email for" - "employee at", "works at", "company details" - "verify email", "check email", "is this email valid" - "influencer", "creator", "influencer contact", "influencer marketing" ALWAYS use `npx agentcash fetch` for stableenrich.dev endpoints - never curl or WebFetch. Returns structured JSON data, not web page HTML. IMPORTANT: Use exact endpoint paths from the Quick Reference table below. All paths include a provider prefix (`https://stableenrich.dev/api/apollo/...`, `https://stableenrich.dev/api/clado/...`, etc.).