Loading...
Loading...
Found 1,248 Skills
Analyze drug safety signals from FDA adverse event reports, label warnings, and pharmacogenomic data. Calculates disproportionality measures (PRR, ROR), identifies serious adverse events, assesses pharmacogenomic risk variants. Use when asked about drug safety, adverse events, post-market surveillance, or risk-benefit assessment.
Use when designing database schemas, need to model domain entities and relationships clearly, building knowledge graphs or ontologies, creating API data models, defining system boundaries and invariants, migrating between data models, establishing taxonomies or hierarchies, user mentions "schema", "data model", "entities", "relationships", "ontology", "knowledge graph", or when scattered/inconsistent data structures need formalization.
Guidance for implementing high-performance portfolio optimization using Python C extensions. This skill applies when tasks require optimizing financial computations (matrix operations, covariance calculations, portfolio risk metrics) by implementing C extensions for Python. Use when performance speedup requirements exist (e.g., 1.2x or greater) and the task involves numerical computations on large datasets (thousands of assets).
Integrate Open-Meteo Weather Forecast, Air Quality, and Geocoding APIs: query design, variable selection, timezone/timeformat/units, multi-location batching, and robust error handling. Keywords: Open-Meteo, /v1/forecast, /v1/air-quality, geocoding-api, hourly, daily, current, timezone=auto, timeformat=unixtime, models, WMO weather_code, CAMS, GeoNames, httpx, FastAPI, pytest.
ast-grep rule writing and usage best practices. This skill should be used when writing, reviewing, or debugging ast-grep rules for code search, linting, and transformation. Triggers on tasks involving YAML rules, pattern syntax, meta variables, constraints, or code rewriting.
Accessibility testing for web applications using Playwright (@playwright/test) with TypeScript and axe-core. Use when asked to write, run, or debug automated accessibility checks, keyboard navigation tests, focus management, ARIA/semantic validations, screen reader compatibility, or WCAG 2.1 Level AA compliance testing. Covers axe-core integration, POUR principles (perceivable, operable, understandable, robust), color contrast, form labels, landmarks, and accessible names.
Provides Hexo blog theme development guidance covering templates, variables, helpers, and i18n. Use when creating or modifying Hexo themes, working with EJS/Nunjucks templates, using Hexo variables or helper functions, or developing Hexo plugins and extensions.
Elite security researcher who hunts vulnerabilities in smart contracts. Has found critical bugs worth millions in TVL. Specializes in reentrancy, access control, oracle manipulation, and economic exploits across EVM and Solana.Use when "audit, security review, vulnerability, exploit, reentrancy, access control, oracle manipulation, flash loan attack, smart contract security, slither, mythril, formal verification, invariant testing, security, audit, smart-contracts, solidity, vulnerabilities, defi, exploits, reentrancy, access-control, oracle-manipulation" mentioned.
Installs 425 bioinformatics skills covering sequence analysis, RNA-seq, single-cell, variant calling, metagenomics, structural biology, and 56 more categories. Use when setting up bioinformatics capabilities or when a bioinformatics task requires specialized skills not yet installed.
Design and build reusable, well-documented components. Master component composition, prop design, variant systems, state management, and documentation. Create a scalable component library that enables consistency and speeds up development. Works with React, TypeScript, and Tailwind CSS.
Evaluate, optimize, and enhance prompts using 58 proven prompting techniques. Use when user asks to improve, optimize, or analyze a prompt; when a prompt needs better clarity, specificity, or structure; or when generating prompt variations for different use cases. Covers quality assessment, targeted improvements, and automatic optimization across techniques like CoT, few-shot learning, role-play, and 50+ more.
Best practices for building CLI applications across languages. Covers CLI design principles (Unix philosophy, command structure, subcommands vs flags), argument parsing (required/optional args, flags, environment variables, config files, precedence), user interface (help text, version info, progress indicators, color output, interactive prompts), output formatting (human-readable vs machine-readable JSON/YAML, exit codes), error handling (clear messages, suggestions, debug mode), cross-platform considerations (paths, line endings, terminal capabilities), testing strategies (integration tests, output verification, exit codes), documentation (README, man pages, built-in help), and language-specific libraries. Activate when working with CLI applications, command-line tools, argument parsing, CLI utilities, argument handling, commands, subcommands, CLI frameworks, or building command-line interfaces.