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Found 1,702 Skills
Comprehensive guide for Biopython - the premier Python library for computational biology and bioinformatics. Use for DNA/RNA/protein sequence analysis, file I/O (FASTA, FASTQ, GenBank, PDB), sequence alignment, BLAST searches, phylogenetic analysis, structure analysis, and NCBI database access.
Before ANY destructive, irreversible, or high-impact action, pause and surface a clear checklist of what's about to happen. This includes: file deletions, database changes, production deployments, mass updates, permission changes, or anything that can't easily be undone. Require explicit confirmation before proceeding. Never auto-execute dangerous operations.
Create and manage Dexie/IndexedDB repositories with type-safe interfaces, converters, and standardized CRUD operations. Use when (1) adding entity storage, (2) implementing save/load/delete operations, (3) designing database schema and indexes, (4) converting between database (Db*) and domain types, (5) handling database errors or migrations, (6) using existing repositories (SettingsRepository, WorkoutsRepository, TemplatesRepository, CustomExercisesRepository, BenchmarksRepository, ActiveWorkoutRepository). Triggers include "database", "repository", "save data", "fetch from database", "delete from storage", "database schema", "database table", "indexes", "migration", "persist", "convert workout", "converter", "buildPartialUpdate", "mock repository", "database error", "bulk operations", "import/export", or specific repository names.
Use this skill when you need to alter the PocketBase database schema - creating, updating, or deleting collections. Never write migration SQL by hand.
Use this skill when creating database schemas or tables for Timescale, TimescaleDB, TigerData, or Tiger Cloud, especially for time-series, IoT, metrics, events, or log data. Use this to improve the performance of any insert-heavy table. **Trigger when user asks to:** - Create or design SQL schemas/tables AND Timescale/TimescaleDB/TigerData/Tiger Cloud is available - Set up hypertables, compression, retention policies, or continuous aggregates - Configure partition columns, segment_by, order_by, or chunk intervals - Optimize time-series database performance or storage - Create tables for sensors, metrics, telemetry, events, or transaction logs **Keywords:** CREATE TABLE, hypertable, Timescale, TimescaleDB, time-series, IoT, metrics, sensor data, compression policy, continuous aggregates, columnstore, retention policy, chunk interval, segment_by, order_by Step-by-step instructions for hypertable creation, column selection, compression policies, retention, continuous aggregates, and indexes.
Structure similarity search with Foldseek. Use this skill when: (1) Finding similar structures in PDB/AFDB databases, (2) Structural homology search, (3) Database queries by 3D structure, (4) Finding remote homologs not detected by sequence, (5) Clustering structures by similarity. For sequence similarity, use uniprot BLAST. For structure prediction, use chai or boltz.
Use the ntion CLI to interact with Notion workspaces — searching, reading, creating, updating, and managing pages, databases (data sources), and block content. Use when the user wants to: (1) search their Notion workspace, (2) query or list databases, (3) read, create, update, archive, or relate pages, (4) read, append, insert, replace, or delete block content on pages, (5) manage Notion authentication, or (6) perform any Notion workspace operation from the terminal. Trigger on mentions of "Notion", "ntion", page/database IDs, or requests involving workspace content management.
Unified intelligent query interface for the CDM DuckDB database. Use this skill when the user wants to query the linkml-coral CDM database. Automatically chooses between fast SQL translation and schema-aware intelligent queries based on complexity. Supports natural language questions, schema exploration, and data analysis.
Expert guidance for SQLModel - the Python library combining SQLAlchemy and Pydantic for database models. Use when (1) creating database models that work as both SQLAlchemy ORM and Pydantic schemas, (2) building FastAPI apps with database integration, (3) defining model relationships (one-to-many, many-to-many), (4) performing CRUD operations with type safety, (5) setting up async database sessions, (6) integrating with Alembic migrations, (7) handling model inheritance and mixins, or (8) converting between database models and API schemas.
Drizzle ORM documentation covering queries, CRUD operations, schema definitions, migrations, caching (50 topics), custom types, and database connections. Includes integrations for PostgreSQL (Neon, Vercel, Supabase, AWS Data API, PlanetScale, Prisma), MySQL (AWS Data API, PlanetScale, TiDB), and SQLite (Bun, Cloudflare D1/Durable Objects, Expo, Turso, OP SQLite). Use when working with Drizzle queries, database schemas, migrations, type-safe SQL, ORM patterns, or connecting to supported databases.
Conducts comprehensive Magento 2 performance analysis and optimization. Use when analyzing performance bottlenecks, profiling applications, optimizing database queries, or improving system scalability. Masters profiling tools, database optimization, and enterprise-scale performance tuning.
Use when querying data with Ecto.Query DSL including where clauses, joins, aggregates, preloading, and query composition. Use for building flexible database queries in Elixir applications.