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Found 2,691 Skills
Comprehensive guide for Biopython - the premier Python library for computational biology and bioinformatics. Use for DNA/RNA/protein sequence analysis, file I/O (FASTA, FASTQ, GenBank, PDB), sequence alignment, BLAST searches, phylogenetic analysis, structure analysis, and NCBI database access.
Complete survival analysis library in Python. Handles right-censored data, Kaplan-Meier curves, and Cox regression. Standard for clinical trial analysis and epidemiology.
Advanced sub-skill for scikit-learn focused on model interpretability, feature importance, and diagnostic tools. Covers global and local explanations using built-in inspection tools and SHAP/LIME integrations.
Manipulation and analysis of planar geometric objects. Based on the widely deployed GEOS library. Provides data structures for points, curves, and surfaces, and standardized algorithms for geometric operations. Use for 2D geometry operations, spatial relationships, set-theoretic operations (intersection, union, difference), point-in-polygon queries, geometric calculations (area, distance, centroid), buffering, simplifying geometries, linear referencing, and cleaning invalid geometries. Essential for GIS operations, spatial analysis, and geometric computations.
Use when user describes a complex project goal, wants to set up multiple skills at once, asks "what skills do I need for X", or needs to manage installed skill bundles. Triggers on multi-skill setup, skill combination, project bootstrapping, or batch skill management.
Real-time serial log monitoring for ESP32 and microcontrollers. Capture device output to a file and monitor logs in real-time. Use when debugging embedded devices, investigating crashes, or monitoring device behavior.
Work with GitHub issues, pull requests, workflows, and repositories using the gh CLI. Use when managing GitHub projects.
OODA loop decision framework (Observe, Orient, Decide, Act). Use for complex decisions, problem-solving, unclear situations, or when someone is jumping to solutions without analysis.
Implement real-time streaming UI patterns for AI chat applications. Use when adding response lifecycle handlers, progress indicators, client effects, or thread state synchronization. Covers onResponseStart/End, onEffect, ProgressUpdateEvent, and client tools. NOT when building basic chat without real-time feedback.
Expert in generating functional options for Go structs using the options-gen library.
Use this skill to plan, write, or run database migrations with the pressly/goose CLI and Go library (SQL/Go migrations, env vars, provider API, embedded migrations).
Expert senior-level Go guidance for architecture, API-first design/codegen, advanced concurrency, performance tuning, testing/quality, cloud-native 12-factor practices, and Go 1.24+ tooling for large-scale systems.