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Found 14,001 Skills
Use when landing a stack of dependent GitHub PRs, merging a PR whose base is another open PR's branch, or a request mentions stacked or dependent PRs. Requires each same-repository dependency chain to use GitHub's official stacked-PR feature before landing.
Run RFDiffusion protein backbone design via NVIDIA NIM. Use for de novo protein backbones, motif scaffolding, binder design, hotspot residues, contigs syntax, diffusion steps, hosted NVIDIA API calls, local Docker deployment, and PDB backbone outputs for ProteinMPNN sequence design.
Run ProteinMPNN inverse folding via NVIDIA NIM to design protein sequences for a target backbone. Use for ProteinMPNN, inverse folding, sequence design, backbone redesign, fixed chains/residues, omit_AAs, sampling temperature, soluble model, hosted NVIDIA API, local Docker, PDB input, and multi-FASTA output.
Generate multiple sequence alignments (MSAs) for protein sequences using the ColabFold MSA-Search NIM. Use for homolog search, UniRef30/ColabFold env searches, A3M or FASTA alignments, paired MSA search for complexes, PDB70 structural templates, hosted NVIDIA API calls, or local Docker deployment. For local deployment, download the databases in parallel with aria2c and launch via NIM_MODEL_NAME (the recommended default fast path, ~14 min vs over 80 min for the built-in downloader); a plain docker run uses the slow built-in downloader.
Use when accelerating existing genomics workflows with NVIDIA Parabricks, improving runtime or price/performance, converting pipeline steps to GPUs, or comparing CPU and GPU workflow outputs. Adds optional GPU steps in-place with runtime toggles (default off). Do NOT use for individual pbrun command routing — use parabricks.
Use this skill for OpenFold2, NVIDIA's BioNeMo NIM microservice for monomer protein structure prediction. Invoke whenever the user mentions OpenFold2, AlphaFold2-like monomer folding, protein sequence-to-structure prediction, A3M MSAs, mmCIF templates, hosted NVIDIA API calls, or local Docker deployment.
Route NVIDIA Parabricks pbrun tools, assess GPU/runtime readiness, and provide version-aware command guidance for FASTQ/BAM processing, RNA-seq, variant calling, BAM QC, and GVCF workflows. Do NOT use for inspecting or accelerating whole pipelines — use genomics-workflow-acceleration.
Perform static application security testing with tools like Semgrep, CodeQL, and SonarQube. Identify security vulnerabilities in source code before deployment. Use when implementing secure SDLC, code review automation, or security gates in CI/CD pipelines.
Reduce AWS spend with rightsizing, autoscaling, commitment planning, and storage lifecycle policies. Use when running FinOps reviews, lowering cloud bills, or improving cost-per-request metrics.
Manage container registries including ECR, ACR, GCR, and Docker Hub. Push and pull images, configure authentication, set up repository policies, and implement image lifecycle management. Use when working with container image storage and distribution.
Build serverless applications on Azure Functions. Configure triggers, bindings, and deployment. Use when implementing serverless workloads on Azure.
Build internal developer platforms (IDPs) with self-service infrastructure, golden paths, and developer portals using Backstage, Crossplane, and score.