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Found 197 Skills
Prioritize drug targets from a ranked gene list (e.g., scRNA-seq DE output) by orchestrating parallel API queries against UniProt, OpenTargets (with integrated DepMap CRISPR essentiality + gnomAD constraint), PubMed, the Human Protein Atlas (HPA), and ChEMBL tool compounds, then re-ranking by a composite score combining protein localization, druggability, disease genetics, tissue specificity (safety), focus-cell-type expression, CRISPR essentiality, LoF safety constraint, and research maturity. Use whenever the user wants to filter, triage, prioritize, or "do due diligence" on a list of candidate genes for drug discovery, especially after a DE / DEG analysis when they say things like "which of these should I follow up on", "filter for druggable targets", "make a target dossier", "rank these for tractability", "annotate these genes for druggability", or "build a target report". Trigger even when the user says just "filter these candidate genes" or hands over a CSV from a DE pipeline.
Guidelines for contributing commands in VS Code extensions. Indicates naming convention, visibility, localization and other relevant attributes, following VS Code extension development guidelines, libraries and good practices
Run an offline ASO audit on pulled App Store metadata and surface keyword gaps using Astro MCP. Use after pulling metadata with asc migrate export or asc localizations download.
Manage auto-renewable subscriptions using the `asc` CLI tool. Use this skill when: (1) Subscription groups: "asc subscription-groups list|create" (2) Subscriptions: "asc subscriptions list|create|submit" (3) Subscription localizations: "asc subscription-localizations list|create" (4) Introductory offers: "asc subscription-offers list|create" (FREE_TRIAL, PAY_AS_YOU_GO, PAY_UP_FRONT) (5) Offer codes: "asc subscription-offer-codes list/create/update" (6) Custom codes: "asc subscription-offer-code-custom-codes list/create/update" (7) One-time codes: "asc subscription-offer-code-one-time-codes list/create/update" (8) User says "subscription group", "subscription tier", "subscription offer code", "custom code", "one-time codes", "free trial", "promo code"
Common utilities and features for Syncfusion Angular components. Use this skill when the user needs to implement animations, drag-and-drop, state persistence, RTL support, localization, globalization, security, templates, and advanced features for Syncfusion Angular components.
Implements Syncfusion WinUI Calendar (SfCalendar) control for date selection in desktop applications. Use this when building date pickers, date selection interfaces (single, multiple, or range), month/year navigation, or calendar views. This skill covers calendar configuration, date restrictions, blackout dates, week numbers, localization, and customization for Windows desktop applications.
Query the DatoCMS Content Delivery API (CDA) — the read-only GraphQL API — using @datocms/cda-client. Use when users ask for GraphQL content reads: fetching posts/pages/projects, filtering by date/text/fields, sorting/order, pagination/load-more, text pattern matching via regex filters, localization and fallback locales, modular content fragments, Structured Text (DAST) with blocks/inline records, responsive images (srcset/blur-up/imgix), SEO metadata (_seoMetaTags, favicons, global SEO), video/Mux fields, draft or preview reads, environment-targeted reads, cache tags via rawExecuteQuery, and Content Link metadata for visual editing. Also use for CDA query type generation with gql.tada or GraphQL Code Generator.
Guide for theming .NET MAUI apps—light/dark mode support, AppThemeBinding, dynamic resources, ResourceDictionary theme switching, and system theme detection. USE FOR: "dark mode", "light mode", "theming", "AppThemeBinding", "theme switching", "ResourceDictionary theme", "dynamic resources", "system theme detection", "color scheme", "app theme". DO NOT USE FOR: localization or language switching (use maui-localization), accessibility visual adjustments (use maui-accessibility), or app icons (use maui-app-icons-splash).
Implement the Syncfusion Angular Mention component for user tagging with autocomplete suggestions in contenteditable elements. Covers data binding (local/remote), filtering, templates, sorting, disabled items, localization, accessibility, and popup customization. Use this when adding @mention or tag functionality to Angular applications, configuring trigger characters, customizing suggestion templates, or ensuring accessibility compliance.
Comprehensive guide for implementing Syncfusion Essential Studio Windows Forms (WinForms) controls in desktop applications. Use this skill when working with Syncfusion WinForms components or Essential Studio WinForms. Covers WinForms installation, localization, high DPI support, and .NET Core compatibility. Helps with adding controls, registering license keys, and troubleshooting WinForms component issues.
Ionic Capacitor mobile app development with Angular, React, or Vue. RevenueCat payments, AdMob ads, i18n localization, onboarding flow, paywall, and Ionic Tabs navigation.
Configures the Unlayer editor — feature flags, appearance, theming, merge tags, design tags, display conditions, special links, HMAC security, file storage, image uploads, localization, custom fonts, validation.