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Found 7 Skills
Provides exact Enzyme → React Testing Library migration patterns for React 18 upgrades. Use this skill whenever Enzyme tests need to be rewritten - shallow, mount, wrapper.find(), wrapper.simulate(), wrapper.prop(), wrapper.state(), wrapper.instance(), Enzyme configure/Adapter calls, or any test file that imports from enzyme. This skill covers the full API mapping and the philosophy shift from implementation testing to behavior testing. Always read this skill before rewriting Enzyme tests - do not translate Enzyme APIs 1:1, that produces brittle RTL tests.
Access BRENDA enzyme database via SOAP API. Retrieve kinetic parameters (Km, kcat), reaction equations, organism data, and substrate-specific enzyme information for biochemical research and metabolic pathway analysis.
Design novel protein therapeutics (binders, enzymes, scaffolds) using AI-guided de novo design. Uses RFdiffusion for backbone generation, ProteinMPNN for sequence design, ESMFold/AlphaFold2 for validation. Use when asked to design protein binders, therapeutic proteins, or engineer protein function.
Foundation skill for autonomous protein engineering via the Amina CLI. Use at session start or after conversation compacting when working with AminoAnalytica's Amina CLI or when you need help using the Amina CLI to do protein engineering tasks like: protein design, structure prediction, binder design, docking, molecular dynamics, enzyme engineering, or any mention of Amina/amina-cli.
Cloud laboratory platform for automated protein testing and validation. Use when designing proteins and needing experimental validation including binding assays, expression testing, thermostability measurements, enzyme activity assays, or protein sequence optimization. Also use for submitting experiments via API, tracking experiment status, downloading results, optimizing protein sequences for better expression using computational tools (NetSolP, SoluProt, SolubleMPNN, ESM), or managing protein design workflows with wet-lab validation.
Ligand-aware protein sequence design using LigandMPNN. Use this skill when: (1) Designing sequences around small molecules, (2) Enzyme active site design, (3) Ligand binding pocket optimization, (4) Metal coordination site design, (5) Cofactor binding proteins. For standard protein design, use proteinmpnn. For solubility optimization, use solublempnn.
Analyze metabolomics data including metabolite identification, quantification, pathway analysis, and metabolic flux. Processes LC-MS, GC-MS, NMR data from targeted and untargeted experiments. Performs normalization, statistical analysis, pathway enrichment, metabolite-enzyme integration, and biomarker discovery. Use when analyzing metabolomics datasets, identifying differential metabolites, studying metabolic pathways, integrating with transcriptomics/proteomics, discovering metabolic biomarkers, performing flux balance analysis, or characterizing metabolic phenotypes in disease, drug response, or physiological conditions.