Total 50,476 skills, Data Processing has 2559 skills
Showing 12 of 2559 skills
Guidance for SPR and BLI binding characterization experiments. Use when: (1) Planning binding kinetics experiments, (2) Troubleshooting poor/no binding signal, (3) Interpreting kinetic data artifacts, (4) Choosing between SPR vs BLI platforms.
Consulta fondos comunes de inversion de Argentina (CAFCI) usando endpoints de lectura de Anduin. Usar cuando el usuario pida fondos por categoria, historico de un fondo, rendimiento por periodo, comparacion entre fondos, rankings de rendimiento, categorias, stats agregadas, fechas disponibles o ficha/detalle de un fondo.
Runs metrics queries against Axiom MetricsDB via scripts. Discovers available metrics, tags, and tag values. Use when asked to query metrics, explore metric datasets, check metric values, or investigate OTel metrics data.
Generate structured research questions, testable hypotheses, and empirical strategies from a topic or dataset
Find or generate a Nimble agent for a task, then run it. Use when the user needs structured web data extraction via Nimble agents/templates.
Extracts frames at regular intervals from dashcam videos to create compact visual summaries of vehicle movement and location changes. This skill should be used when users need motion trajectory analysis, want to optimize dashcam storage by 90%+, need quick visual review of hours of footage, or want to create visual timelines of trips.
Corporate bond analysis: credit spreads (OAS, Z-spread, G-spread), credit ratings, migration matrices, callable structures, private credit.
Perform comprehensive gene enrichment and pathway analysis using gseapy (ORA and GSEA), PANTHER, STRING, Reactome, and 40+ ToolUniverse tools. Supports GO enrichment (BP, MF, CC), KEGG, Reactome, WikiPathways, MSigDB Hallmark, and 220+ Enrichr libraries. Handles multiple ID types (gene symbols, Ensembl, Entrez, UniProt), multiple organisms (human, mouse, rat, fly, worm, yeast), customizable backgrounds, and multiple testing correction (BH, Bonferroni). Use when users ask about gene enrichment, pathway analysis, GO term enrichment, KEGG pathway analysis, GSEA, over-representation analysis, functional annotation, or gene set analysis.
Provide comprehensive clinical interpretation of somatic mutations in cancer. Given a gene symbol + variant (e.g., EGFR L858R, BRAF V600E) and optional cancer type, performs multi-database analysis covering clinical evidence (CIViC), mutation prevalence (cBioPortal), therapeutic associations (OpenTargets, ChEMBL, FDA), resistance mechanisms, clinical trials, prognostic impact, and pathway context. Generates an evidence-graded markdown report with actionable recommendations for precision oncology. Use when oncologists, molecular tumor boards, or researchers ask about treatment options for specific cancer mutations, resistance mechanisms, or clinical trial matching.
Regression Analysis Helper - Auto-activating skill for Data Analytics. Triggers on: regression analysis helper, regression analysis helper Part of the Data Analytics skill category.
Identify and prioritize causal variants at GWAS loci using statistical fine-mapping and locus-to-gene predictions. Computes posterior probabilities for causal variants, links variants to genes via L2G predictions, annotates functional consequences, and suggests validation strategies. Use when asked to fine-map GWAS loci, prioritize causal variants, identify credible sets, or link GWAS signals to causal genes.
Production-ready VCF processing, variant annotation, mutation analysis, and structural variant (SV/CNV) interpretation for bioinformatics questions. Parses VCF files (streaming, large files), classifies mutation types (missense, nonsense, synonymous, frameshift, splice, intronic, intergenic) and structural variants (deletions, duplications, inversions, translocations), applies VAF/depth/quality/consequence filters, annotates with ClinVar/dbSNP/gnomAD/CADD via ToolUniverse, interprets SV/CNV clinical significance using ClinGen dosage sensitivity scores, computes variant statistics, and generates reports. Solves questions like "What fraction of variants with VAF < 0.3 are missense?", "How many non-reference variants remain after filtering intronic/intergenic?", "What is the pathogenicity of this deletion affecting BRCA1?", or "Which dosage-sensitive genes overlap this CNV?". Use when processing VCF files, annotating variants, filtering by VAF/depth/consequence, classifying mutations, interpreting structural variants, assessing CNV pathogenicity, comparing cohorts, or answering variant analysis questions.