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Found 1,529 Skills
Universal SQL performance optimization assistant for comprehensive query tuning, indexing strategies, and database performance analysis across all SQL databases (MySQL, PostgreSQL, SQL Server, Oracle). Provides execution plan analysis, pagination optimization, batch operations, and performance monitoring guidance.
Overview of Experimental MVCC feature - snapshot isolation, versioning, limitations
SQLite file format, B-trees, pages, cells, overflow, freelist that is used in tursodb
Overview and information about Neki, the sharded Postgres product by PlanetScale. Load when working with Neki-related tasks and the need to scale or shard postgres.
Plan and review MySQL/InnoDB schema, indexing, query tuning, transactions, and operations. Use when creating or modifying MySQL tables, indexes, or queries; diagnosing slow/locking behavior; planning migrations; or troubleshooting replication and connection issues.
Change Data Capture - architecture, entrypoints, bytecode emission, sync engine integration, tests
Query NHGRI-EBI GWAS Catalog for SNP-trait associations. Search variants by rs ID, disease/trait, gene, retrieve p-values and summary statistics, for genetic epidemiology and polygenic risk scores.
Access AlphaFold's 200M+ AI-predicted protein structures. Retrieve structures by UniProt ID, download PDB/mmCIF files, analyze confidence metrics (pLDDT, PAE), for drug discovery and structural biology.
Direct REST API access to PubMed. Advanced Boolean/MeSH queries, E-utilities API, batch processing, citation management. For Python workflows, prefer biopython (Bio.Entrez). Use this for direct HTTP/REST work or custom API implementations.
Access ClinPGx pharmacogenomics data (successor to PharmGKB). Query gene-drug interactions, CPIC guidelines, allele functions, for precision medicine and genotype-guided dosing decisions.
Query PubChem via PUG-REST API/PubChemPy (110M+ compounds). Search by name/CID/SMILES, retrieve properties, similarity/substructure searches, bioactivity, for cheminformatics.
Query openFDA API for drugs, devices, adverse events, recalls, regulatory submissions (510k, PMA), substance identification (UNII), for FDA regulatory data analysis and safety research.